glp 1 triple agonist Schematic illustration of monoagonists, dual agonists and When the Breakthrough Obesity G-Agonist
Description
This benefit is also supported by trials such as LEADER, SUSTAIN-6, and EXSCEL, in which the reduction in MACE was significant among those with established ASCVD

Brain Res (2012) 1473:20413
Poster presented at: ObesityWeek 2025

[12] Adverse effects [edit] Preclinical, phase I, and phase II clinical trials indicated that tirzepatide exhibits adverse effects similar to those of other established GLP-1 receptor agonists, such as dulaglutide (sold as Trulicity) and semaglutide (sold as Wegovy, Ozempic, and Rybelsus)
P., Geiss, L

"Wegovys New Uses, Cost, and Safety." Axios , 28 July 2025, Wang, L., et al
