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in one of them, in patients with type 2 diabetes, four months of treatment with semaglutide reduced carotid artery thickness, a clinical marker of atherosclerosis, by 13 percent

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Lastly, a high-fat diet supplemented with 10% guar gum over a duration of 12 weeks is introduced to C57B mice, resulting in the production of short-chain fatty acids through colonic fermentation that stimulate GLP-1 release, thereby enhancing glucose clearance [28]