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But they can also help prevent the disease in people who have insulin resistance or prediabetes
Morbach C, Strk S

If you are currently taking medications, have existing health conditions, are pregnant or nursing, or are considering any major changes to your health regimen, consult your physician before starting GLP-1 treatment or any new prescription medication

PMCID: PMC5286837

Pending successful completion, FDA approval could come as early as 2027, which would make retatrutide the first approved triple-agonist medication

While Metformin improves insulin sensitivity and helps control appetite, GLP-1 medications (like semaglutide or tirzepatide) slow digestion and enhance feelings of fullness
