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In December 2024, the FDA approved tirzepatide (Zepbound) to treat moderate to severe obstructive sleep apnea in adults with obesity

10.1210/en.2012-1937

One concern thats genuine: muscle loss

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That can lead to an uncomfortable experience later, especially if digestion is already slower or the person is sensitive to THC

Glucagon-like peptide-1 (GLP-1) receptor agonists are a class of medications primarily used to manage type 2 diabetes and, more recently, obesity