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According to the Wegovy SmPC, gastrointestinal side effects including nausea, vomiting, and diarrhoea are common, particularly during dose escalation

How GLP-1 Works Without Breaking Your Budget GLP-1 receptor agonists function by slowing gastric emptying and increasing satiety signals to the brain's appetite centers

The timeline for noticeable effects varies based on individual metabolism, injection site, and body composition

Beier, Larry S

Titration of a drug is a common method used by healthcare professionals, especially for drugs that affect nerve or hormonal pathways or drugs with a narrow therapeutic range between the effective dose and toxic dose

While not explicitly labelled as GLP-1 friendly, these moves align with the underlying principles of the trend
