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Existing mental health or life circumstances Depression, anxiety, chronic stress, poor sleep, relationship difficulties and other significant life changes may occur alongside treatment
Kidney Issues: Semaglutide can affect kidney function, especially in people with pre-existing kidney conditions
Phase 2 trials studied up to 12 mg weekly, but no approved dosing regimen exists in the UK
The STEP 8 clinical trial compared the effect of weekly subcutaneous semaglutide vs liraglutide (daily) in obese and overweight patients without type 2 diabetes
doi: 10.1016/j.jaad.2019.02.067, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] 43.Krajewski PK, Sanz-Motilva V, Flores Martinez S, Solera M, Ochando G, Jfri A, et al
Ideally performed in sinus rhythm
