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GLP-1 Receptor Agonists Reduce Colorectal Cancer Risk in IBD Populations Cancer Network Staff Tim Cortese , Russ Conroy Retrospective data showed that GLP-1 receptor agonist use was associated with a 51% reduction in colorectal cancer odds among patients with inflammatory bowel disease

Lean mass is a broad category that includes skeletal muscle, bone density, connective tissue, and water
The team had already shown that GLP1-RAs can reduce alcohol intake in rats (5)

Targeting GIP as well as GLP-1 is the distinguishing idea behind dual agonists such as tirzepatide
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