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Jayne Hornung, of MMIT, says the existence of the Reta black market is "horrifying." But, in a twisted way, it has only helped boost expectations for Lilly's next big drug

Why this matters It reinforces that endpoint language matters (missing non-inferiority no efficacy) It keeps the spotlight on amylin + GLP-1 biology as a serious strategy It shows how obesity therapeutics is becoming a multi-platform race, not a single-drug race Novos message appears clear: the company still sees a meaningful role for CagriSema, and is continuing development with future studies (including REDEFINE 11 / higher-dose exploration)

Aims/hypothesis Prediabetes (HbA1c 3947 mmol/mol [5.76.4%] or fasting glucose 5.66.9 mmol/l) is associated with elevated risks of microvascular and macrovascular complications

He acknowledged economic pressure, health and wellness, and younger consumers drinking differently

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