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these drugs include glucagon-like peptide-1 (GLP-1) receptor agonists and dipeptidyl peptidase 4 (DPP-4) inhibitors [13, 14]

Also, as an anabolic hormone, insulin promotes fat storage, and chronic hyperinsulinemia, commonly observed in T2DM, further stimulates lipogenesis while suppressing lipolysis, thereby counteracting BW reduction

Additionally, the doseeffect relationship was not assessed, and the follow-up duration of the included studies was relatively short, with most lasting up to 14 months

A loss of glycemic control can have immediate health consequences, including hyperglycemia symptoms like increased thirst, frequent urination, and fatigue

[DOI] [PubMed] [Google Scholar] 126.Barbieri M., Marfella R., Esposito A., Rizzo M.R., Angellotti E., Mauro C., Siniscalchi M., Chirico F., Caiazzo P., Furbatto F., et al

Weight Regain After GLP-1-Based Therapy Discontinuation: Failure, Physiology, or Follow-Up Gap