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TSH (thyroid-stimulating hormone): Hypothyroidism can mimic or worsen weight gain

Hyperglycaemia has been suggested to cause increased expression of inflammation-related genes in macrophages

The role of GIP in the regulation of GLP-1 satiety and nausea
Abandoning exercise when the medication stops working A common pattern is that people exercise consistently during treatment, then stop exercising once the medication is discontinued, often because returned appetite and fatigue make it harder to find motivation
In an unusual move, GLP manufacturers have asked for vision loss lawsuits to be consolidated in a group litigation called a multidistrict litigation

FDA's stated rationale: it found no clinical need for 503B outsourcing facilities to compound these medications from bulk substances, given that FDA-approved products are commercially available