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[DOI] [PMC free article] [PubMed] [Google Scholar] 43.Ayton SL, Gulsin GS, McCann GP, et al

My digestion was on point, and I felt less inflamed overall

A 2025 database study published in the International Journal of Impotence Research found that non-diabetic obese men prescribed semaglutide for weight loss had a 4.5-fold higher risk of erectile dysfunction and nearly double the risk of testosterone deficiency compared to matched controls not taking the drug

Physiological changes in body composition during weight loss also affect the rate of continued weight reduction

However, most cases were mild to moderate and occurred primarily during the dose escalation period