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GSK-3 inhibition through GLP-1R allosteric activation mediates the neurogenesis promoting effect of P7C3 after cerebral ischemic/reperfusional injury in mice

Dart RJ, Zlatareva I, Vantourout P, et al

While this early research was done with animals, the results are promising

Time below therapeutic range increased by 0.8% ( p = 0.25), time above therapeutic range increased by 1.3% ( p = 0.04), and INR standard deviation increased by 0.03 ( p = 0.051)

Crystal structure of the 2 adrenergic receptor-Gs protein complex

While a comprehensive discussion of the literature is outside the scope of this review, the data presented so far certainly demonstrate how quickly our understanding of the potential role of GLP-1 RAs as a strategy for healthy aging is progressing