glp-1 hfpef Receptor Agonists Among Patients With Overweight or Obesity, Diabetes, and on SGLT2 Inhibitors Impact of GLP-1 receptor agonists

This first wave of GLP-1s were commercially successful (Victoza saw peak sales of ~$3.8B in 2018), but results were modest relative to todays market

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In essence, GLP-1 RAs like liraglutide may improve cognitive function and reduce dementia risk in some patients, but more research is needed to confirm these findings due to variability in study outcomes

Additionally, when GLP1R knockout mice were used to validate the impact of exenatide and liraglutide, no increase in calcitonin secretion or C-cell hyperplasia was observed

Diabetes Metab 32(1):713

Masks, tubing, cushions, and filters are all covered by Medicare on a replacement schedule - but you typically need to request them