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However, clinical studies have not demonstrated clinically significant alterations in the bioavailability or therapeutic effect of these agents when co-administered with semaglutide

Benoit SC, Clegg DJ, Seeley RJ, Woods SC

Important precautions Depression and anxiety disorders Both medicines can cause an increase in suicidal thoughts or self-harm, particularly when first starting treatment or changing doses

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These effects combine to reduce calorie intake and support sustainable weight loss

In clinical trials, Wegovy was found to reduce risks of cardiovascular events by 20%in higher weight patients