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These medications act by mimicking GLP-1, causing increased feelings of fullness and reduced appetite, leading to weight loss for some people

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[DOI] [PubMed] [Google Scholar] 233.Ostendorf D.M., Melanson E.L., Caldwell A.E., Creasy S.A., Pan Z., MacLean P.S., Wyatt H.R., Hill J.O., Catenacci V.A

Elevated serum lipopolysaccharide (LPS) indicates a compromised gut barrier and is linked to plaque formation and rupture in AS [33]
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36 Endogenous GLP-1 has a short half-life (1-2 min), with only 10% reaching systemic circulation due to rapid degradation, which has driven the development of degradation-resistant GLP-1RAs
