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According to the American Diabetes Association's Standards of Medical Care in Diabetes, proper injection technique and systematic site rotation are essential for optimal medication absorption and to prevent lipohypertrophy (thickening of fatty tissue) or lipoatrophy (loss of fatty tissue) at injection sites

suffer from CIC.* *Estimated IBS-C/CIC sufferers within the U.S

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Rotate your injection site each week to prevent lipohypertrophy (thickened skin from repeated injections in the same spot)