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Consequently, up to 66% of liver transplant recipients are affected by diabetes which has profound impact on liver allograft and patient survival

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While these findings offer reassurance in cases of inadvertent exposure to GLP-1 medications during the first trimester of pregnancy, larger trials are needed for more conclusive results

Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes

In the SYNERGY-NASH trial, a phase 2 study involving participants with metabolic dysfunctionassociated steatohepatitis (MASH) and moderate or severe fibrosis, treatment with tirzepatide for 52 weeks was more effective than placebo in achieving resolution of MASH without worsening fibrosis [146]