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To gain further insight into the mechanism of degradation we used mass spectrometry to analyse the pGLP-1 and eGLP-1 cleavage products

What data exists suggests that weight is typically regained after discontinuation, often rapidly

Circulation 116 (12), 14131423

Endoscopic pyloric injection of botulinum toxin A for the treatment of refractory gastroparesis

It lowers your metabolism and increases hunger hormones (like ghrelin), making it biologically difficult to maintain weight loss