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GLP-1 restores the intestinal barrier function in DSS-induced colitic mice DSS-induced local and systemic proinflammatory mediators led to the disruption of the intestinal barrier

Nausea, constipation, and gastrointestinal discomfort are common during dose escalation and often improve with time

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49,50 Although we observed significant differences in weight loss at all time points, our small sample size may have affected the statistical significance of some of our endpoints

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