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Current Research Evidence Animal Studies Multiple studies in mice have demonstrated significant effects of MOTS-c treatment: 1. Age-Diverse Performance Studies: MOTS-c treatment (15 mg/kg/day) for two weeks improved physical performance in mice of different ages (2, 12, 22, and 23.5 months)[5][2]

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Semaglutide alleviated reserpine induced histopathological and immunohistopathological changes in spinal cord of rats evidenced by a remarkable rise in immuno-expression of cluster of differentiation 163 (CD163) contrary to a significant diminution in CD86 level as compared with reserpine group

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