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doi: 10.3390/microorganisms10102061

Other Safety Considerations Several additional safety topics are relevant to the clinical use of orforglipron: Gallbladder events: GLP-1 receptor agonists have been associated with increased rates of cholelithiasis and cholecystitis, likely mediated by rapid weight loss altering bile composition and gallbladder motility

Health care companies are also subject to competitive forces that may result in price discounting, may be thinly capitalized and susceptible to product obsolescence

The p values were estimated using 2 tests for categorical variables and t tests for continuous variables

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