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[DOI] [PubMed] [Google Scholar] 32.Perez-Garcia A, Hurtado-Carneiro V, Herrero-De-Dios C, Dongil P, Garcia-Maurino JE, Sanchez MD, et al

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A recent study showed a serotonin 1B receptor circuit (5-HTR 1B AgRP paraventricular nucleus circuit) for appetite suppression in mice, which suggested that 5-HTR 1B is a potential new target in 5-HT-based weight-loss therapies

10 Similarly, another systematic review and meta-analysis of 764 randomised controlled trials also showed a reduction in all-cause mortality with use of GLP-1RAs (odds ratio [OR] 0.88

According to the MHRA-approved Summary of Product Characteristics (SmPC), the most commonly reported side effects include nausea, vomiting, diarrhoea, abdominal pain, and constipation

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