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Both medications can typically be used together when needed to manage gastrointestinal symptoms

For male fertility, research is even more sparse

People with obesity or diabetes can have low vitamin B12 (especially if they take metformin, a common diabetes drug)

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However, there have been relatively few studies on the mechanism of GLP-1RAs in the treatment of chronic pain

Sajad Zalzala, Board-certified Family Medicine Physician and Medical Advisor at SkinnyRx Key Takeaways GLP-1s affect the hypothalamus, which is responsible for regulating your perception of heat and cold