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Banek CT, Knuepfer MM, Foss JD, Fiege JK, Asirvatham-Jeyaraj N, Van Helden D, et al

GLP-1 Receptor Agonists: Nonglycemic Clinical Effects in Weight Loss and Beyond

The authors searched for randomised clinicals trials of GLP-1 RA medications (albiglutide, dulaglutide, exenatide, liraglutide, lixisenatide, or semaglutide) that also reported adverse events of gallbladder or biliary diseases

Triple agonists target three different receptors, the GLP-1R, the GIPR, and the GCGR, producing complementary but independent impacts on blood glucose and body weight
Cowie CC, Casagrande SS, Menke A (2018) Diabetes in America

Liraglutide is a previous generation GLP-1 and future studies will use more powerful current generation therapies like semaglutide or tirzepatide
