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During arousal and orgasm, compounds are released that can affect male biology: - Copulins:fatty acids in vaginal secretions, often described aspheromone-like compounds, that may act as chemosignals influencing male hormonal responses and sexual motivation - Lactobacilli:a healthy vaginal microbiome supports microbial balance and may also contribute to overall urogenital health 3

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Although the pathophysiology is incompletely understood, there are common mechanisms between sarcopenia and the phenomenon of accelerated ageing seen in diabetes mellitus