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We used the search terms stroke, GLP-1, GLP-1 receptor agonist, diabetes, and neuroprotection from 1 January 2011 to 1 August 2021

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These drugs have shown efficacy beyond glycaemic regulation, including significant weight loss, cardiovascular protection, and possible advantages for renal function

These types of studies establish confidence in the outcomes, as neither the scientists nor the participants are aware of who receives actual medication versus a placebo during the trial

In these cases, anaesthetists take additional precautions to reduce aspiration risk, and post-operative resumption is carefully planned based on individual recovery