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However, symptom heterogeneity and overlap with other non-immunological food sensitivities, combined with the absence of standardized diagnostic criteria and validated testing protocols, continue to obscure its classification

Rather than directly suppressing appetite through the nervous system, it works on the brain's reward pathways targeting the areas that drive cravings and emotional eating

First, the study was conducted at a single institution (a university hospital), with a small sample size, and was limited to facilities accredited by the Japan Diabetes Society, which raises concerns about the generalizability of the findings

na podstawie: PAP, EMA PRZEJD DO: OBESITOLOGIA

We conducted a sensitivity analysis using an alternative, more restrictive specification of cirrhosis variable, defined based on 2 outpatient or 1 inpatient ICD codes for cirrhosis, and excluded patients with a FIB-4 score of less than 1.3 to further reduce any possible misclassification (eTable 6 in Supplement 1)