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Diabetologia 66(5):813825 Lingvay I, Desouza CV, Lalic KS, Rose L, Hansen T, Zacho J et al (2018) A 26-Week randomized controlled trial of Semaglutide once Daily Versus Liraglutide and Placebo in patients with type 2 diabetes suboptimally controlled on Diet and Exercise with or without Metformin

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While semaglutide doesnt directly raise or lower potassium, it can impact your blood sugar and fluid balance, which could influence potassium levels indirectly

In some cases, spironolactone may even cause weight loss by eliminating excess water from the body