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David Smith, urologist and co-founder of medical device company BladGo Medical, told Drugwatch
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INS-1 832/3 GLP-1R KO cells were seeded onto 12-well plates and transfected as detailed in Table 3

Efforts to engineer insulin itself to overcome such defects are inherently limited, as the compact size and densely functional binding surface of insulin limit its engineerability for targeting mutant IRs

BMC Physiol, 11:12

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