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Rationale Obesity remains a major global health challenge, severely affecting metabolic and cardiovascular health

Pendulum, a research-based health company, has launched a groundbreaking new product - a probiotic supplement designed to naturally suppress appetite

Glucagon-like peptide-1 receptor agonists (GLP-1 RAs), initially developed for glycaemic control in patients with type 2 diabetes, have demonstrated significant cardiometabolic benefits

This was attributed to insulin deficiency and vomiting-induced acid loss and bicarbonate retention

SSIB cases associated with GLP-1RAs were identified and analyzed through disproportionality analysis using the information component

Results The final report includes 50 studies