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If you feel muted on your GLP-1, it might be worth investigating other ways to recalibrate your relationship with dopamine

(12) used Cre-lox technology to delete the gene encoding the GLP-1R specifically in the CNS (nestin- Cre Glp1r fl/fl mice) or in the peripheral nervous system ( Phox2b-Cre Glp1r fl/fl mice)

Marx N, Davies MJ, Grant PJ et al

That is a meaningful concern

Cotadutide (GLP-1/Glucagon dual receptor agonist) modulates hypothalamic orexigenic and anorexigenic neuropeptides in obese mice

B6.Cg-Tg(Tek-cre)1Ywa/J ( Tie2 -Cre), B6.SJL-Tg( Vil1 -Cre)997Gum/J ( Vil -Cre), and B6.SJL-Ptprc a Pepc b /BoyJ mice (for bone marrow transplant) were obtained from The Jackson Laboratory