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A 4% drop in absolute LBM accompanying a 12% drop in body weight gives roughly 20% of weight loss as 'lean tissue.' Batsis reports closer to 35% and as Langer makes clear later in this piece, the gap between those numbers is partly explained by what DXA actually counts as 'lean

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doi: 10.1152/physrev.00034.2006 37 MarsoSPDanielsGHBrown-FrandsenKKristensenPMannJFNauckMAet al

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GLP-1 triggers in vivo actions by binding to G proteins to activate cellular pathways that lead to various effects in the central nervous areas

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