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Reduced appetite can also make it harder to fuel properly and get the right nutrients to support intense training, recovery and muscle maintenance

The primary endpoint should be measurable, sensitive to change, clinically meaningful, and be able to be quantified consistently

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Saxenda European Medicines Agency

Some analyses, especially in more symptomatic populations, place the threshold a bit higher, closer to 1520 points for a change that patients clearly perceive as important

When to Contact Your Doctor While Ozempic breath is usually just an annoying side effect, severe or worsening symptoms should not be ignored
