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9: Correra A, Mauriello A, Cetoretta V, Maratea AC, Riegler L, Di Sarno I, Giallauria F, Guerra F, Russo V, D'Andrea A

Nat Med 2024

Most people who see results notice small changes after 8 to 12 weeks of daily use combined with diet and exercise

Co-treatment of 4d (A2-thio-imidazole derivative), a novel TGR5 agonist, and Sitagliptin (DPP-4 inhibitor) exhibited a GLP-1 secretion and glucose-lowering effect in animal models, while this compound alone exhibits only a slight 1.3-fold increase in GLP-1 secretion [182]

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