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The larger molecular size and diverse quaternary structure enhance their interaction with specific protein pockets, making peptides and protein drugs have better biological activity and lower toxicity than small molecules
As evident, both liraglutide and retatrutide can induce significant weight loss

Hp infection seems to enhance the release of leptin, which originates predominantly from the adipocytes and less from the gastric glands, and it is not clear how the Hp in the stomach could affect the release of this peptide
Common side effects such as nausea, vomiting, and food aversions can further reduce intake, increasing this risk

While cramping can be uncomfortable, it rarely requires stopping treatment
