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Metabolic Support and Muscle Preservation Some peptides like tirzepatide also target GIP receptors, further aiding fat and energy metabolism
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Based on current clinical trial data, tirzepatide (Zepbound/Mounjaro) at the 15 mg dose produces the highest average weight loss approximately 2022% of body weight, or around 48 lbs on average in the SURMOUNT-1 trial

Contraves label contains a boxed warning found on all antidepressants: a risk of suicidal thoughts and actions in children, adolescents, and young adults when used for depression
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Alternative 2 pathways Tirzepatide Mounjaro and Zepbound Dual GLP-1 + GIP agonist with FDA approval
