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M.LiC.-s.R.MantzorosC

Effects of liraglutide on depressive behavior in a mouse depression model and cognition in the probe trial of Morris water maze test

PMID: 21454562

Impact of GLP-1 and GLP-1 receptor agonists on cardiovascular risk factors in type 2 diabetes

Despite the absence of adverse cardiovascular effects has been confirmed, this benefit was not verified in an integrated analysis of 12 controlled, randomized, short-term clinical trials (12-52 weeks) comparing exenatide with placebo or insulin [72]

In a mid-stage trial it showed weight loss of up to 24.2% at 48 weeks