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And check our guide on the best fiber supplements for GLP-1 users if this is an ongoing issue

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Mike Haney: So we're going to talk a lot today about GLP-1s, but I want to start by talking about obesity in general because I want to sort of frame this conversation you know, in this modern age of people being able to go online and get a GLP-1 prescription in 10 minutes, or micro-dosing it, or taking it for all sorts of different clinical implications

Here's where it gets really concerning

In isolated islets, VSG mice had changes in their genetic and functional signature favoring calcium signaling and insulin secretion (45)

DPP IV inhibitor blocks mescalineinduced scratching and amphetamineinduced hyperactivity in mice