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Description
Shaking creates air bubbles and can denature the peptide through mechanical stress

A total of 156 trial participants were randomized to receive daily liraglutide (30 mg) ( n = 80) or placebo ( n = 76) for 52 weeks
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Prescription GLP-1 receptor agonists - semaglutide and tirzepatide - mimic this signal at pharmaceutical concentrations, producing the significant appetite suppression and weight loss outcomes that made them famous

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None of this is a reason for alarm about a very common and usually short-lived effect
