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Long-term safety concerns, particularly regarding potential risks to the thyroid and gallbladder, are still being explored

2018 Jul;14(7):390-403

The goal is not only to improve efficacy, but to differentiate products in a crowded and high-stakes market

In people with T2DM, exenatide treatment reduced serum levels of inflammatory proteins linked to AD risk (88), and studies with liraglutide or sitagliptin (a DPP-IV inhibitor that elevates GLP-1 levels) reported lower cytokine levels and modest cognitive improvements (89)

Tirzepatide is the first in a class of drugs called dual GLP-1/GIP receptor agonists that activate the receptor for another gut hormone, glucose-dependent insulinotropic polypeptide (GIP), in addition to the GLP-1 receptor

Evaluate the Time Commitment GLP-1 agonists: Ongoing use of medication is required for sustained results