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While some medications may retain partial potency beyond their expiration dates, there is no reliable way for patients or clinicians to determine how much active ingredient remains in expired tirzepatide without laboratory analysis

How It Works: GLP-1 agonists bind to GLP-1 receptors in the brain, particularly in areas such as the hypothalamus, to reduce hunger and increase satiety

This may help explain why protein is often considered one of the most satiating nutrients

Legro, MD, FACOG, can be reached at [email protected]

38,39 That said, there are also reports of no significant impact of exenatide on BMD or fracture risk in T2D, 40 with subsequent meta-analyses also yielding conflicting outcomes

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