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In addition, data obtained in preclinical models and small cohorts suggest that the GLP1RAs liraglutide may downregulate PCSK9, a major inhibitor of LDL-receptor expression associated with the development of atherosclerosis [25, 26]

2019;316(2):C13553

Pre-treatment screening identifies those who need cholecystectomy or conservative management before weight loss therapy begins

Cross-border e-commerce platforms, including JD Health and Alibaba Health, are improving nationwide accessibility of metabolic health supplements and protein nutrition products

doi:10.1007/s00259-019-04409-1 151

PEG modification increased the stability of protein and peptide drugs, increased the solubility, reduced the immunogenicity, prolonged the residence time in blood, reduced the protease degradation, and reduced the frequency of drug use