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These effects include the reduction of inflammation and oxidative stress, vasodilation, decreased arterial stiffness, and a reduction in myocardial fibrosiskey factors in the pathophysiology of HFpEF

While existing GLP-1 medications have shown greater weight loss than Lillys oral medication, this option targets both weight loss and type 2 diabetes in patients.

Updating our priors after the one-year anniversary of our original GLP-1 Primer

The data were analyzed using both mean differences (MDs) and standardized mean differences (SMDs) with 95% CIs and odds ratios (ORs) with 95% CIs

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The researchers are planning a randomized trial to test whether benefits extend beyond weight to cardiovascular and metabolic markers