sglt2 inhibitors and glp-1 receptor agonists together Effect of combination treatment with glucagon-like peptide-1 sodium-glucose cotransporter-2 on incidence of cardiovascular and serious renal events: population based cohort study Frontiers | A decade of
Description
Patients were being treated with metformin-based background therapy and were considered at high risk for a cardiovascular event [56]

Nature Rev Disease Primers

LUPKIN: GLP-1
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GLP-1 medications, or glucagon-like peptide-1 receptor agonists, treat type 2 diabetes when other medications havent sufficiently managed blood sugar levels

Multiple randomised, placebo-controlled trials have tested GLP-1 drugs as add-on therapy to insulin in people with T1D, and the picture that emerges is consistent, if modest: meaningful weight loss, real reductions in daily insulin needs, and improvements in CGM time in range

Cloning the GLP-1 receptor demanded very technically demanding experiments which Thorens managed to do single-handedly
