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In contrast, no benefits on the rate of decline in glomerular filtration rate have been seen in trials of DPP-4 inhibitors, perhaps because the renal actions of DPP-4 inhibitors are primarily mediated by potentiation of SDF-1, not GLP-1

Patients who reduced the frequency of GLP-1 dosing (from weekly to every other week) were able to maintain their weight loss and metabolic syndrome gains, as reported in this case series

There have been concerns that GLP-1RAs may increase the risk of intestinal obstruction

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Once a relatively obscure class of drugs prescribed for people with diabetes, GLP-1s have now shown an impressive ability to treat obesity, which affects...

Evidence-based comparison of CagriSema (amylin + GLP-1) and tirzepatide (GIP + GLP-1) for obesity, including REDEFINE and SURMOUNT trial data.