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Over time, obstructive sleep apnea can cause serious cardiac disease and serious neurologic problems, in terms of mental awareness and falling asleep easily during the day, Ren-Fielding said

doi: 10.1038/24884

It carried out its own meta-analysis of 91 clinical trials across GLP-1 drug development programmes involving more than 100,000 subjects to improve its estimate of the risk, and also conducted a review of healthcare claims data to compare the risk of intentional self-harm with SGLT2 inhibitors used to treat diabetes

Endocrinology 153: 30543065

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These prices place brand-name GLP-1 medications out of reach for most people without insurance coverage or manufacturer copay assistance programs