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A previous study has shown that the combination of GLP-1R agonist and angiotensin receptor blocker (ARB) increases natriuresis compared to GLP-1R agonist alone in Otsuka LongEvans Tokushima Fatty rats, a model of obese type 2 diabetes [68]

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As this review explores the glycogenic and thermogenic effects of GLP-1, the remainder of this section will focus on T2DM and obesity, two disease states directly impacted by glycogenesis and thermogenesis

Ipamorelin: Mechanism and Research Background Ipamorelin is a synthetic pentapeptide classified as a growth hormone-releasing peptide (GHRP)
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