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Description
The excess of circulating FFAs results in their increased flow in the liver and their storage, mainly in the form of triglycerides [4]
Evening cortisol spikes suppress melatonin, destabilize glucose, disrupt SCFA rhythms, and weaken satiety signals, driving nighttime snacking

The most common problems were gastrointestinal, including nausea and vomiting

The letter authors urged clinicians to be aware of the adverse effects of drugs like Ozempic on the small intestine

According to a study published in the Journal of the American Medical Association , patients on GLP-1 therapies experience significantly higher rates of gastrointestinal adverse events compared with non-users

If we want berberine to compete with something like Ozempic, researchers need to find a way to increase the dose , increase the potency/bioavailability , and reduce those side effects
