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Tirzepatide was more efficacious in reducing body weight
The fermentation of fiber in the gut leads to the production of short-chain fatty acids, which can stimulate GLP-1 secretion

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We also describe the development of incretin-based pharmacotherapy, starting with exendin- 4 and ending with the identification of multi-incretin hormone receptor agonists, which appear to be the next major step in the fight against T2DM and obesity

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