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discontinue sulfonylurea when starting glp-1 receptor agonist GLP1-RA and SGLT2-i: Implementation and Insulin Deescalation Strategies | Cardiovascular Drugs and Therapy Mechanism of action of sulfonylureas
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2021;13(372): m4573

doi:10.1111/j.1476-5381.2012.01971.x 11

2013;369:145-154) found that intensive lifestyle intervention focused on weight loss did not reduce cardiovascular events in a large cohort of adults with overweight/obesity and type 2 diabetes

The majority of these therapies aim to replicate or inhibit the effects of various gut hormones such as GLP-1, GIP, amylin, and glucagon [27, 28]

You might know them by brand names like Ozempic, Wegovy, Mounjaro or Zepbound

Butler AE, Janson J, Bonner-Weir S, Ritzel R, Rizza RA, Butler PC